Oncology ; 54 suppl 1: User Name Password Sign In. Eniluracil is not a prodrug of 5-FU or an anticancer agent, rather, it potentiates the effects of 5-FU by causing virtually complete inhibition of DPD. Patrick G. This neurotoxicity is due to an inactive metabolite generated during conversion of tegafur to 5-FU. Patients prefer tablets as long as they work as well and are as safe as IV treatment, because they are easier to take and are more convenient.
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Oral Chemotherapeutic Agents for Colorectal Cancer
This combination has also been tested with oral leucovorin [ 37 ]. Comparative monthly cost of administering 5-fluorouracil 5-FU as a day infusion or capecitabine as oral therapy. Schedule dependent efficacy of camptothecins in models of human cancer. Oral chemotherapy has been widely thought to have a potential for cost savings when compared to intravenous chemotherapy. Anderson Cancer Center [ 27 ].